NaPDI | Compound details

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Natural products containing this compound

Enantiomer of compound
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Compound has enantiomers
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Metabolite of compounds
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Compound has metabolites

3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-F3DjaQ	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: CBDD-AMMC	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	cannabidiol-dimethyl ether
NPDI-XBXjow	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: THC-AMMC	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	delta-9-tetrahydrocannabinol
NPDI-b-kubA	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: CBN-AMMC	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	cannabinol
NPDI-8jlF2g	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: CBD-AMMC	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	cannabidiol
NPDI-payj8A	Kratom (Mitragyna speciosa)	Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay	Mitragynine inhibition of CYP2D6	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	mitragynine
NPDI-iDzluw	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: CBDV-AMMC	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	cannabidivarin
NPDI-y29wsw	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.	Recombinant: CBDM-AMMC	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2D6		3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin	3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin	cannabidiol-dimethyl ether

ID	Subject of Study	Name
NPDI-ieYYdA	Cannabis (Cannabis sativa)	Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.
NPDI-FfN_4A	Kratom (Mitragyna speciosa)	Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay