Mitragynine inhibition of CYP2D6 CSV JSON

In Vitro Enzyme Inhibition Experiment

Mitragynine inhibition of CYP2D6

Inhibition was detected.  Cutoff used —

Not specified

  • CYP2D6 4173631

Recombinant expression system Not available
Cytochrome B5 Not available

Results

Quinidine was used as the positive control
(Table 2, Figure 2)

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

1.5 µM

Commercially available

30 min

NADPH regenerating system