In Vitro Enzyme Inhibition Experiment

CBD-dimethyl ether

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabidiol-dimethyl ether

resorufin -7999853

  • CYP1A1 4173297

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Results

%inhibitionpre-incubation at estimated 50 μM at 20 min (Figure 2).
IC50pre-incubation at 0 min (Table 1)
IC50pre-incubation at 20 min - 7.68
Kinact/KI converted from /min/mmol to /min/μM (Table 2)
All other values from Table 2.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Commercially available

200 µL

30 min

NADPH

20 µL

180 µL

5 min

NADPH with precipitant