Percent inhibition of CYP1A2 by epicatechin gallate CSV JSON

In Vitro Enzyme Inhibition Experiment

Percent inhibition of CYP1A2 by epicatechin gallate

Inhibition was detected.  Cutoff used — not provided

7-ethoxyresorufin -7999995

epicatechin gallate

resorufin -7999853

  • CYP1A2 4312402

Recombinant expression system Not available
Cytochrome B5 Not available

Results

Percent inhibition at 100 µM as estimated from Fig. 3 is presented.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.

CYP: 40 pmol/mL

In-house preparation

0.5 mL

10 min

NADPH regenerating system

Not available

Not available

1 µM

0-100 µM