- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450
In Vitro Enzyme Inhibition Experiment
Percent inhibition of CYP1A2 by epicatechin gallate
Inhibition was detected. Cutoff used — not provided
- CYP1A2 4312402
Recombinant expression system Not available
Cytochrome B5 Not available
Percent inhibition at 100 µM as estimated from Fig. 3 is presented.
|Sample||Compound measured||Value||Measurement||Study sequence||Additional information||N replicates|
Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.
CYP: 40 pmol/mL
NADPH regenerating system