In Vitro Enzyme Inhibition Experiment

Cannabidiol

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabidiol (cbd)

resorufin -7999853

  • CYP1A1 4173297

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Results

% inhibition estimated from Figure 2 at 20 min.
IC50 at 0 min - 0.671
IC50 at 20 min (table 1)
Kinact/KI converted from /min/mmol to /min/μM (table 2).
All other values from Table 2.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Commercially available

200 µL

30 min

NADPH

20 µL

180 µL

5 min

NADPH with precipitant