In Vitro Enzyme Inhibition Experiment

CBD-UGT2B7 Inhibition

Inhibition was detected.  Cutoff used — Not specified

ethanol

cannabidiol (cbd)

ethyl glucuronide

  • UGT2B7

Cell system Human cryopreserved hepatocytes

Results

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

In-house preparation

100 μL

45 min

MgCl2

UDPGA

25 mM

5 min

No NADPH with no precipitant

0, 5, 10,15 mg/L