- Natural product: Cannabis (Cannabis sativa)
- Associated study: Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines.
In Vitro Transporter Induction Experiment
Down regulation of P-gp (mRNA) by Cannabidiol
Down Regulation was detected. Cutoff used —
N/A
- P-gp (ABCB1)
Cell system Jar
Results
figure 5
Sample | Compound measured | Value | Measurement | Additional information | N replicates |
---|---|---|---|---|---|
cannabidiol | 0.5 ± 0.2-fold | Change from vehicle control Mean ± SD | P-value: P < 0.05 | 6 |
Experimental Conditions
mRNA expression
Cannabis
24h, 48h, 72h
qRT-PCR, 2 CT method