- Natural product: Goldenseal (Hydrastis canadensis)
- Associated study: Tetrandrine Potentiates the Hypoglycemic Efficacy of Berberine by Inhibiting P-Glycoprotein Function
In Vitro Transporter Inhibition Experiment
Reduced Efflux of Berberine Through P-gp
Inhibition was detected. Cutoff used — not specified
berberine 19012197
- P-gp (ABCB1)
Cell system Caco-2 cells
Results
46.5/74.6 Fig 3
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
5 x 10^4/cm^2
14
30-45
3 h
20 μM
2 μM
Sigma-Aldrich Co