Inhibition of MATE1 by (-)-epigallocatechingallate CSV JSON

In Vitro Transporter Inhibition Experiment

Inhibition of MATE1 by (-)-epigallocatechingallate

Inhibition was detected.  Cutoff used — NA

metformin 1503297

(-)-epigallocatechin gallate

  • MATE1 (SLC47A1)

Transfected / siRNA knock-out / injected cells HEK293 transfected cells

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Cell Culture Conditions

7.0 x 10^5 cells/well

12-well poly-D-lysine coated plates

48 h

Assay Conditions

10 min

37 deg C

8

10 µM

100 µM

Prof. Toshiyuki Kan (Department of Synthetic Organic and Medicinal Chemistry, University of Shizuoka, Japan)

Control Experiment