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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-WsMb-g Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Metformin uptake in MATE2-K cells In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • MATE2-K (SLC47A2)
metformin
NPDI-GaLUxw Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of MATE1 by (-)-epigallocatechingallate In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • MATE1 (SLC47A1)
metformin (-)-epigallocatechin gallate
NPDI-DGEDfw Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of MATE2-K by (-)-epigallocatechingallate In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • MATE2-K (SLC47A2)
metformin (-)-epigallocatechin gallate
NPDI-nm2fYg Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of OCT2 by Green Tea In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • OCT2 (SLC22A2)
metformin green tea leaf
NPDI-GdcFMg Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of MATE2-K by Green Tea In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • MATE2-K (SLC47A2)
metformin green tea leaf
NPDI-cpRc8Q Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of MATE1 by Green Tea In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • MATE1 (SLC47A1)
metformin green tea leaf
NPDI-eejWAQ Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Metformin uptake in MATE1 cells In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • MATE1 (SLC47A1)
metformin
NPDI-bVuJYQ Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of OCT2 by (-)-epigallocatechin gallate In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • OCT2 (SLC22A2)
metformin (-)-epigallocatechin gallate
NPDI-27Q7-A Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of OCT1 by (-)-epigallocatechin gallate In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • OCT1 (SLC22A1)
metformin (-)-epigallocatechin gallate
NPDI-b-Qyxw Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Metformin uptake in OCT2 cells In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • OCT2 (SLC22A2)
metformin
NPDI-F3BK2A Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Metformin uptake in OCT1 cells In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • OCT1 (SLC22A1)
metformin
NPDI-8cPLyw Green Tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of OCT1 by Green Tea In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • OCT1 (SLC22A1)
metformin green tea leaf

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