Inhibition of CYP2B6 by (-)-Epigallocatechin Gallate in HLM (IC50 Determination) CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP2B6 by (-)-Epigallocatechin Gallate in HLM (IC50 Determination)

Inhibition was detected.  Cutoff used — IC50 determination

bupropion 750982

hydroxybupropion 4037950

  • CYP2B6 4308333

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.1 mg/mL

Commercially available

100 µL

20 min

NADPH

Not available

Not available

62 µM

1-218 µM