bupropion
InChIKey: SNPPWIUOZRMYNY-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-fWaGRg licoricidin Inhibition of CYP enzymes by licoricidin Inhibition of CYP2B6 by Licoricidin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion licoricidin
NPDI-uh21Qg licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2B6 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion licochalcone a
NPDI-mWgNew Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Inhibition of CYP2B6 by G. inflata Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion ethanolic extract of licorice g. inflata
NPDI-oFLPrw Green tea (Camellia sinensis) Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes Inhibition of CYP2B6 by (-)-Epigallocatechin Gallate in HLM (Ki Determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion (-)-epigallocatechin gallate
NPDI-ZNG6KQ glycycoumarin Inhibition of CYP enzymes by glycycoumarin Inhibition of CYP2B6 by Glycycoumarin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion glycycoumarin
NPDI-DVoeXQ Licorice (Glycyrrhiza glabra) Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents Inhibition of CYP2B6 by G. glabra Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion ethanolic extract of licorice g. glabra
NPDI-FQmbtQ Licorice (Glycyrrhiza uralensis) Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents Inhibition of CYP2B6 by G. uralensis Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion ethanolic extract of licorice g. uralensis
NPDI-KMW0mA Green tea (Camellia sinensis) Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes Inhibition of CYP2B6 by (-)-Epigallocatechin Gallate in HLM (IC50 Determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion (-)-epigallocatechin gallate

Compound information from external resources

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