Inhibition of CYP2B6 by Licoricidin CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP2B6 by Licoricidin

Inhibition was detected.  Cutoff used —

50 % inhibition

bupropion 750982

licoricidin

hydroxybupropion 4037950

  • CYP2B6 4308333

Cell fraction Pooled human liver microsomes -7999662

Results

Figure 3

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

10 min

NADPH

12 µM

4.25 μg/mL