licochalcone a
InChIKey: KAZSKMJFUPEHHW-DHZHZOJOSA-N

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Compound information managed by NaPDI

  • Licorice (Glycyrrhiza inflata)
  • Licorice (Glycyrrhiza uralensis)
  • Licorice (Glycyrrhiza glabra)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-CAfs7A licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP3A4 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
midazolam 1'-hydroxymidazolam licochalcone a
NPDI-4WGfNA licochalcone a Inhibition of CYP enzymes by licochalcone a Negligible inhibition of CYP2E1 by Licochalcone A In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
chloroxazone 6-hydroxychloroxazone licochalcone a
NPDI-AVsEiw licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2C9 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
tolbutamide hydroxymethyltolbutamide licochalcone a
NPDI-eb9bKA licochalcone a Inhibition of CYP enzymes by licochalcone a Negligible inhibition of CYP2A6 by Licochalcone A In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2A6
coumarin 7-hydroxycoumarin licochalcone a
NPDI-NUpDbg licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP3A4 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
testosterone 6beta-hydroxytestosterone licochalcone a
NPDI-Rx5N8Q licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2A1 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
phenacetin acetaminophen licochalcone a
NPDI-DJNbNQ licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2C8 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine licochalcone a
NPDI-HNpTng licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2C19 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
mephenytoin, (s)- 4-hydroxymephenytoin, (s)- licochalcone a
NPDI-uh21Qg licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2B6 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2B6
bupropion hydroxybupropion licochalcone a
NPDI-mJF8xw licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2D6 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2D6
dextromethorphan dextrorphan licochalcone a
NPDI-l1_dTA Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza inflata Characterization of Material

Compound information from external resources

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