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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-eDM7DQ Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Negligible inhibition of CYP2E1 by G. inflata Licorice extract In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
chloroxazone 6-hydroxychloroxazone ethanolic extract of licorice g. inflata
NPDI-4WGfNA licochalcone a Inhibition of CYP enzymes by licochalcone a Negligible inhibition of CYP2E1 by Licochalcone A In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
chloroxazone 6-hydroxychloroxazone licochalcone a
NPDI-vgJV_w Licorice (Glycyrrhiza uralensis) Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents Negligible inhibition of CYP2E1 by G. uralensis Licorice extract In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
chloroxazone 6-hydroxychloroxazone ethanolic extract of licorice g. uralensis
NPDI-Vt7rHw Goldenseal (Hydrastis canadensis) In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes CYP2E1 Experiment In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP2E1
chloroxazone goldenseal root extract
NPDI-QkbxIg Licorice (Glycyrrhiza glabra) Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents Negligible inhibition of CYP2E1 by G. glabra Licorice extract In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2E1
chloroxazone 6-hydroxychloroxazone ethanolic extract of licorice g. glabra

Compound information from external resources

Resource Identifier
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