NaPDI | Compound details

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Natural products containing this compound

Enantiomer of compound
None listed

Compound has enantiomers
None listed

Metabolite of compounds
None listed

Compound has metabolites

6-hydroxychloroxazone

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-4WGfNA	licochalcone a	Inhibition of CYP enzymes by licochalcone a	Negligible inhibition of CYP2E1 by Licochalcone A	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2E1		chloroxazone	6-hydroxychloroxazone	licochalcone a
NPDI-eDM7DQ	Licorice (Glycyrrhiza inflata)	Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents	Negligible inhibition of CYP2E1 by G. inflata Licorice extract	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2E1		chloroxazone	6-hydroxychloroxazone	ethanolic extract of licorice g. inflata
NPDI-vgJV_w	Licorice (Glycyrrhiza uralensis)	Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents	Negligible inhibition of CYP2E1 by G. uralensis Licorice extract	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2E1		chloroxazone	6-hydroxychloroxazone	ethanolic extract of licorice g. uralensis
NPDI-QkbxIg	Licorice (Glycyrrhiza glabra)	Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents	Negligible inhibition of CYP2E1 by G. glabra Licorice extract	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP2E1		chloroxazone	6-hydroxychloroxazone	ethanolic extract of licorice g. glabra
NPDI-Vt7rHw	Goldenseal (Hydrastis canadensis)	In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes	CYP2E1 Experiment	In Vivo Interaction	negative — No Effect (based on bioequivalence limits)	CYP2E1		chloroxazone		goldenseal root extract

ID	Subject of Study	Name
NPDI-oEAKVw	licochalcone a	Inhibition of CYP enzymes by licochalcone a
NPDI-UmIRAQ	Licorice (Glycyrrhiza inflata)	Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents
NPDI-Lm3PvA	Licorice (Glycyrrhiza uralensis)	Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents
NPDI-8SkM4A	Licorice (Glycyrrhiza glabra)	Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents
NPDI-ftEv0g	Goldenseal (Hydrastis canadensis)	In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes

Compound information from external resources

Resource	Identifier
Google search	TZFWDZFKRBELIQ-UHFFFAOYSA-N