Negligible inhibition of CYP2E1 by G. uralensis Licorice extract CSV JSON

In Vitro Enzyme Inhibition Experiment

Negligible inhibition of CYP2E1 by G. uralensis Licorice extract

Negligible Inhibition was detected.  Cutoff used —

> 100 µg/ml

chloroxazone

6-hydroxychloroxazone

  • CYP2E1 4173608

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

10 min

NADPH

15 µM

11 concentrations from 0.005–250 μg/mL