amodiaquine
InChIKey: OVCDSSHSILBFBN-UHFFFAOYSA-N

Need public description.

Compound information managed by NaPDI


None listed

None listed

None listed

ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-SUW3zQ Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Inhibition of CYP2C8 by G. inflata Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine ethanolic extract of licorice g. inflata
NPDI-TGg2kA Licorice (Glycyrrhiza glabra) Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents Inhibition of CYP2C8 by G. glabra Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine ethanolic extract of licorice g. glabra
NPDI-955SOw Licorice (Glycyrrhiza uralensis) Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents Inhibition of CYP2C8 by G. uralensis Licorice extract In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine ethanolic extract of licorice g. uralensis
NPDI-E0u5ug glycycoumarin Inhibition of CYP enzymes by glycycoumarin Inhibition of CYP2C8 by Glycycoumarin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine glycycoumarin
NPDI-DJNbNQ licochalcone a Inhibition of CYP enzymes by licochalcone a Inhibition of CYP2C8 by Licochalcone A In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine licochalcone a
NPDI-5_OSjg isoliquiritigenin Inhibition of CYP enzymes by isoliquiritigenin Inhibition of CYP2C8 by Isoliquiritigenin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine isoliquiritigenin
NPDI-Rtoc6Q licoricidin Inhibition of CYP enzymes by licoricidin Inhibition of CYP2C8 by Licoricidin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine licoricidin
NPDI-fleVog glycyrrhetinic acid Inhibition of CYP enzymes by glycyrrhetinic acid Inhibition of CYP2C8 by 18-beta-Glycyrrhetinic acid In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine glycyrrhetinic acid
NPDI-XeGihA Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Weak Inhibition of Paynantheine for CYP2C8 In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine paynantheine
NPDI-U-ajPw Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Weak Inhibition of 7-hydroxymitragynine for CYP2C8 In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine 7-hydroxymitragynine
NPDI-o56vpA Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Weak Inhibition of Corynantheidine for CYP2C8 In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine corynantheidine
NPDI-JqmF7w Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Inhibition of Speciociliatine for CYP2C8 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine speciociliatine
NPDI-B_7tOA Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Weak Inhibition of Speciogynine for CYP2C8 In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine speciogynine
NPDI-J2PdQQ Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Inhibition of Mitragynine for CYP2C8 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine mitragynine
NPDI-s8ImuA Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Control Positive Inhibition for CYP2C8 In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine montelukast
NPDI-Hh_vaQ Green tea (Camellia sinensis) Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes Inhibition of CYP2C8 by (-)-Epigallocatechin Gallate in HLM (IC50 Determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine (-)-epigallocatechin gallate
NPDI-rnQE5Q Green tea (Camellia sinensis) Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A activities in human liver and intestinal microsomes Inhibition of CYP2C8 by (-)-Epigallocatechin Gallate in HLM (Ki Determination) In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine (-)-epigallocatechin gallate

Compound information from external resources

Resource Identifier
Google search OVCDSSHSILBFBN-UHFFFAOYSA-N