glycyrrhetinic acid
InChIKey: MPDGHEJMBKOTSU-PMTKVOBESA-N

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Compound information managed by NaPDI

  • Licorice (Glycyrrhiza glabra)
  • Licorice (Glycyrrhiza uralensis)
  • Licorice (Glycyrrhiza inflata)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-92ORyA glycyrrhetinic acid Inhibition of CYP enzymes by glycyrrhetinic acid Inhibition of CYP3A4 by 18-beta-Glycyrrhetinic acid In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
testosterone 6beta-hydroxytestosterone glycyrrhetinic acid
NPDI-Ik84yA Licorice (Glycyrrhiza glabra) Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice) Glycyrrhetinic acid - CAR Activation Experiment - 1 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
glycyrrhetinic acid
NPDI-BSD3Hg Licorice (Glycyrrhiza glabra) Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice) Glycyrrhetinic acid - GR Activation Experiment - 1 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
glycyrrhetinic acid
NPDI-fCU6fg Licorice (Glycyrrhiza glabra) Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice) Glycyrrhetinic acid - hPXR Activation Experiment - 1 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
glycyrrhetinic acid
NPDI-fleVog glycyrrhetinic acid Inhibition of CYP enzymes by glycyrrhetinic acid Inhibition of CYP2C8 by 18-beta-Glycyrrhetinic acid In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine glycyrrhetinic acid
NPDI-l1_dTA Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza inflata Characterization of Material
NPDI-ebe-GA Licorice (Glycyrrhiza uralensis) Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza uralensis Characterization of Material
NPDI-XhhVrA Licorice (Glycyrrhiza glabra) Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza glabra L. Characterization of Material

Compound information from external resources

Resource Identifier
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