isoliquiritigenin
InChIKey: DXDRHHKMWQZJHT-FPYGCLRLSA-N

Need public description.

Compound information managed by NaPDI

  • Licorice (Glycyrrhiza glabra)
  • Licorice (Glycyrrhiza uralensis)
  • Licorice (Glycyrrhiza inflata)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-5_OSjg isoliquiritigenin Inhibition of CYP enzymes by isoliquiritigenin Inhibition of CYP2C8 by Isoliquiritigenin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C8
amodiaquine n-desethylamodiaquine isoliquiritigenin
NPDI-uw6NfQ isoliquiritigenin Inhibition of CYP enzymes by isoliquiritigenin Inhibition of CYP3A4 by Isoliquiritigenin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
testosterone 6beta-hydroxytestosterone isoliquiritigenin
NPDI-lFzdxg isoliquiritigenin Inhibition of CYP enzymes by isoliquiritigenin Inhibition of CYP2C9 by Isoliquiritigenin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
tolbutamide hydroxymethyltolbutamide isoliquiritigenin
NPDI-VwDDFg Licorice (Glycyrrhiza glabra) Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice) Isoliquiritigenin - hPXR Activation Experiment - 1 In Vitro Nuclear Receptor Induction positive — In Vitro Nuclear Receptor Induction
  • Pregnane X receptor (PXR)
isoliquiritigenin
NPDI-l1_dTA Licorice (Glycyrrhiza inflata) Cytochrome P450 inhibition by licorice species Glycyrrhiza inflata and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza inflata Characterization of Material
NPDI-ebe-GA Licorice (Glycyrrhiza uralensis) Cytochrome P450 inhibition by licorice species Glycyrrhiza uralensis and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza uralensis Characterization of Material
NPDI-XhhVrA Licorice (Glycyrrhiza glabra) Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents Chemical characterization of Licorice, Glycyrrhiza glabra L. Characterization of Material

Compound information from external resources

Resource Identifier
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