In Vitro Enzyme Inhibition Experiment

rCYP2C9: CBN-diclofenac

Inhibition was detected.  Cutoff used — Not specified

diclofenac 1124300

cannabinol (cbn)

4'-hydroxydiclofenac

  • CYP2C9 4309227

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 No

Results

Tables 2 and 3

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

2 pmol

Commercially available

250 μL

20 min

MgCl2
NADPH regenerating system

5 min

NADPH with precipitant