Inhibition of OATP1B1 by Green Tea CSV JSON

In Vitro Transporter Inhibition Experiment

Inhibition of OATP1B1 by Green Tea

Inhibition was detected.  Cutoff used — NA

atorvastatin

green tea leaf

  • OATP1B1 (SLCO1B1)

Transfected / siRNA knock-out / injected cells HEK293 transfected cells

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Cell Culture Conditions

7.0 x 10^5 cells/well

12-well poly-D-lysine coated plates

48 h

Assay Conditions

10 min

37 deg C

2.5 µM

0.01-10 % v/v

Healthya green tea (Kao Corp., Tokyo, Japan)

Control Experiment