- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein
In Vitro Transporter Inhibition Experiment
Inhibition of OATP1B1 by Green Tea
Inhibition was detected. Cutoff used — NA
- OATP1B1 (SLCO1B1)
Transfected / siRNA knock-out / injected cells HEK293 transfected cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
7.0 x 10^5 cells/well
12-well poly-D-lysine coated plates
48 h
10 min
37 deg C
2.5 µM
0.01-10 % v/v
Healthya green tea (Kao Corp., Tokyo, Japan)