green tea inhibition of SULT1A3 using ritodrine as the substrate CSV JSON

In Vitro Enzyme Inhibition Experiment

green tea inhibition of SULT1A3 using ritodrine as the substrate

Inhibition was detected.  Cutoff used — Not available

ritodrine 1313200

green tea leaf

ritodrine sulfate ester

  • SULT1A3

Recombinant expression system E.coli
Cytochrome B5 No

Results

The above result was observed at 10% of green tea. At green tea 1 and 5%, ritodrine sulfation was significantly inhibited by approximately 25% (estimated from Fig. 2B) and > 95% (P < 0.01 for both), respectively.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

In-house preparation

50 µL

10 min (pH 6.8)

PAPS

3000 µM

1, 5, and 10%