Weak Inhibition of 11-hydroxylation of delta-8-THC by ketoconazole CSV JSON

In Vitro Enzyme Inhibition Experiment

Weak Inhibition of 11-hydroxylation of delta-8-THC by ketoconazole

Negligible Inhibition was detected.  Cutoff used —

Not provided

ketoconazole

11-hydroxy-delta-8-tetrahydrocannabinol

  • CYP3A

Cell fraction Pooled human liver microsomes -7999662

Results

Table 1

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

10 microG

Commercially available

20 min

NADPH
NADPH regenerating system

64 µM

10 µM