NaPDI | Compound details

Need public description.

Natural products containing this compound

Enantiomer of compound
None listed

Compound has enantiomers
None listed

Metabolite of compounds

delta-8-tetrahydrocannabinol

Compound has metabolites
None listed

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-M8-Oxw	Cannabis (Cannabis sativa)	Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes	Weak Inhibition of 11-hydroxylation of delta-8-THC by ketoconazole	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP3A		delta-8-tetrahydrocannabinol	11-hydroxy-delta-8-tetrahydrocannabinol	ketoconazole
NPDI-42-g8Q	Cannabis (Cannabis sativa)	Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes	Inhibition of 11-hydroxylation of delta-8-THC by sulfaphenazole	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C		delta-8-tetrahydrocannabinol	11-hydroxy-delta-8-tetrahydrocannabinol	sulfaphenazole
NPDI-RCBEtw	Cannabis (Cannabis sativa)	Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes	Weak Inhibition of 11-hydroxylation of delta-8-THC by 7,8-benzoflavone	In Vitro Enzyme Inhibition	negative — In Vitro Enzyme Negligible Inhibition	CYP1A		delta-8-tetrahydrocannabinol	11-hydroxy-delta-8-tetrahydrocannabinol	alpha-naphthoflavone

ID	Subject of Study	Name
NPDI-Rvn9SQ	Cannabis (Cannabis sativa)	Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes