sulfaphenazole
InChIKey: QWCJHSGMANYXCW-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-tjxX2A Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-sulfaphenazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C9
cannabidiol 6α-oh-cannabidiol sulfaphenazole
NPDI-v2Z25g Kratom (Mitragyna speciosa) Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities POS. CONTROL: Inhibition of CYP2C9 by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
6’deoxyluciferin (luciferin h) luciferin sulfaphenazole
NPDI-H6ZqbA Kratom (Mitragyna speciosa) Evaluation of selected Malaysian medicinal plants on phase I drug metabolizing enzymes, CYP2C9, CYP2D6 and CYP3A4 activities in vitro POS. CONTROL: Inhibition of CYP2C9 by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
6’deoxyluciferin (luciferin h) luciferin sulfaphenazole
NPDI-t32_Ig Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Control Positive Inhibition for CYP2C9 In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • CYP2C9
diclofenac 4'-hydroxydiclofenac sulfaphenazole
NPDI-5Fz7kg Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 7-alpha-hydroxylation of delta-8-THC by sulfaphenazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C
delta-8-tetrahydrocannabinol 7-alpha-hydroxy-delta-8-tetrahydrocannabinol sulfaphenazole
NPDI-42-g8Q Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Inhibition of 11-hydroxylation of delta-8-THC by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C
delta-8-tetrahydrocannabinol 11-hydroxy-delta-8-tetrahydrocannabinol sulfaphenazole
NPDI-Yr3jng Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 8-beta-hydroxylation of delta-9-THC by sulfaphenazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C
delta-9-tetrahydrocannabinol 8-beta-hydroxy-delta-9-tetrahydrocannabinol sulfaphenazole
NPDI-qmmKqA Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Inhibition of 11-hydroxylation of delta-9-THC by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C
delta-9-tetrahydrocannabinol 11-hydroxy-delta-9-tetrahydrocannabinol sulfaphenazole
NPDI-uxfWFg Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 8-hydroxylation of cannabinol by sulfaphenazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C
cannabinol 8-hydroxycannabinol sulfaphenazole
NPDI-8flCOQ Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Inhibition of 11-hydroxylation of cannabinol by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C
cannabinol 11-hydroxycannabinol sulfaphenazole

Compound information from external resources

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