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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-z3MwKw Cannabis (Cannabis sativa) Drug Approval Package: Epidiolex (Cannabidiol) Clobazam Effect on 6-OH-CBD In Vivo Interaction negative — No Effect (based on bioequivalence limits)
6α-oh-cannabidiol clobazam
NPDI-RPqAvQ Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-quinidine In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2D6
cannabidiol 6α-oh-cannabidiol quinidine
NPDI-otngFw Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-ketoconazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
cannabidiol 6α-oh-cannabidiol ketoconazole
NPDI-tjxX2A Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-sulfaphenazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2C9
cannabidiol 6α-oh-cannabidiol sulfaphenazole
NPDI-jJ11Ig Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-omeprazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
cannabidiol 6α-oh-cannabidiol omeprazole

Compound information from external resources

Resource Identifier
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