Clobazam Effect on 6-OH-CBD CSV JSON

Natural product: Cannabis (Cannabis sativa)
Associated study: Drug Approval Package: Epidiolex (Cannabidiol)

In Vivo Interaction Study

Clobazam Effect on 6-OH-CBD

No Effect (based on bioequivalence limits) was detected.

Object compound

6α-oh-cannabidiol

Precipitant

clobazam

Study GWEP1543

Results

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Experimental Conditions

Study design

Fixed-sequence
Parallel
Multiple dosing

Population

Demographic characteristics

Females
Healthy volunteers
Males

Number of subjects

Population additional information

Arm 2, Group 2

Drug or Natural Product Administration

Object Administration — 6α-oh-cannabidiol

Administration route

Oral

Formulation

Solution

Total daily dose

1500 mg

Interval/frequency

750 mg BID

Duration

21 days

Precipitant Administration — clobazam

Administration route

Oral

Formulation

Not specified

Total daily dose

10 mg

Interval/frequency

5 mg BID

Duration

21 days

Natural Product Characteristics

Year sourcing was completed