omeprazole
InChIKey: SUBDBMMJDZJVOS-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-nzhlHQ Goldenseal (Hydrastis canadensis) Repeated administration of berberine inhibits cytochromes P450 in humans CYP2C19 Experiment In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP2C19
omeprazole berberine
NPDI-fw_WMw Cannabis (Cannabis sativa) Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19. Inhibition of CYP2C19 by Cannabidiol In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
omeprazole 5-hydroxyomeprazole cannabidiol
NPDI-2YTaDQ Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 CBD Inhibition on CYP2C19 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
omeprazole 5-hydroxyomeprazole cannabidiol
NPDI-z-n9lA Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 THC Inhibition on CYP2C19 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
omeprazole 5-hydroxyomeprazole delta-9-tetrahydrocannabinol
NPDI-kU7TmQ Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 11-OH-THC Inhibition on CYP2C19 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
omeprazole 5-hydroxyomeprazole 11-hydroxy-delta-9-tetrahydrocannabinol
NPDI-jJ11Ig Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-omeprazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C19
cannabidiol 6α-oh-cannabidiol omeprazole

Compound information from external resources

Resource Identifier
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