NaPDI | Compound details

Need public description.

Natural products containing this compound

Enantiomer of compound
None listed

Compound has enantiomers
None listed

Metabolite of compounds

omeprazole

Compound has metabolites
None listed

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-fw_WMw	Cannabis (Cannabis sativa)	Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19.	Inhibition of CYP2C19 by Cannabidiol	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C19		omeprazole	5-hydroxyomeprazole	cannabidiol
NPDI-2YTaDQ	Cannabis (Cannabis sativa)	Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450	CBD Inhibition on CYP2C19	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C19		omeprazole	5-hydroxyomeprazole	cannabidiol
NPDI-z-n9lA	Cannabis (Cannabis sativa)	Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450	THC Inhibition on CYP2C19	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C19		omeprazole	5-hydroxyomeprazole	delta-9-tetrahydrocannabinol
NPDI-kU7TmQ	Cannabis (Cannabis sativa)	Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450	11-OH-THC Inhibition on CYP2C19	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C19		omeprazole	5-hydroxyomeprazole	11-hydroxy-delta-9-tetrahydrocannabinol

ID	Subject of Study	Name
NPDI-9V_SXw	Cannabis (Cannabis sativa)	Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19.
NPDI-lalKkg	Cannabis (Cannabis sativa)	Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450

Compound information from external resources

Resource	Identifier
Google search	CMZHQFXXAAIBKE-UHFFFAOYSA-N