quinidine
InChIKey: LOUPRKONTZGTKE-LHHVKLHASA-N

Need public description.

Compound information managed by NaPDI


None listed

None listed

None listed

None listed
ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-RPqAvQ Cannabis (Cannabis sativa) Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes 6-alpha-OH-CBD-quinidine In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2D6
cannabidiol 6α-oh-cannabidiol quinidine
NPDI-FnVAqw Kratom (Mitragyna speciosa) Evaluation of selected Malaysian medicinal plants on phase I drug metabolizing enzymes, CYP2C9, CYP2D6 and CYP3A4 activities in vitro POS. CONTROL: Inhibition of CYP2D6 by quinidine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2D6
ethylene glycol ester of luciferin 6’methyl ether (luciferin me-ege) luciferin quinidine
NPDI-d0noGQ Kratom (Mitragyna speciosa) Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities POS. CONTROL: Inhibition of CYP2D6 by quinidine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2D6
ethylene glycol ester of luciferin 6’methyl ether (luciferin me-ege) luciferin quinidine
NPDI-WL-VKw Kratom (Mitragyna speciosa) The inhibitory effects of mitragynine on P-glycoprotein in vitro Control inhibition of P-gp digoxin transport by quinidine In Vitro Transporter Inhibition (Control experiment) positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
 digoxin quinidine
NPDI-ye4dPw Kratom (Mitragyna speciosa) The inhibitory effects of mitragynine on P-glycoprotein in vitro Down regulation of P-gp mRNA expression by 1 µM quinidine In Vitro Transporter Induction positive — In Vitro Transporter Down Regulation
  • P-gp (ABCB1)
 quinidine
NPDI-4AITQg Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Control Positive Inhibition for CYP2D6 In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • CYP2D6
dextromethorphan dextrorphan quinidine

Compound information from external resources

Resource Identifier
Google search LOUPRKONTZGTKE-LHHVKLHASA-N