POS. CONTROL: Inhibition of CYP2D6 by quinidine CSV JSON

In Vitro Enzyme Inhibition Experiment

POS. CONTROL: Inhibition of CYP2D6 by quinidine

Inhibition was detected.  Cutoff used — Not specified.



  • CYP2D6 4173631

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Positive control


Positive control

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Positive controls sulfaphenazole, quinidine, and ketoconazole were purchased from Sigma Chemicals (St. Louis, USA). This assay was carried out using the P450-Glo™ Screening Systems from Promega, USA.

The minus-P450 wells (using luciferin-free water) were negative controls.

Commercially available

100 µL

65 min

NADPH regenerating system

Not available

Not available

0.02-200 µM