digoxin
InChIKey: LTMHDMANZUZIPE-PUGKRICDSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-wur44g Green tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein P-gp mediated digoxin transport in Caco-2 cells In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • P-gp (ABCB1)
 digoxin
NPDI-PRsP6g Green tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of P-gp by Green Tea In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
 digoxin green tea leaf
NPDI-6qDdNA Green tea (Camellia sinensis) Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein Inhibition of P-gp by (-)epigallocatecin gallate In Vitro Transporter Inhibition positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
 digoxin (-)-epigallocatechin gallate
NPDI-cxxGnA Kratom (Mitragyna speciosa) The inhibitory effects of mitragynine on P-glycoprotein in vitro Control P-gp digoxin transport In Vitro Transporter Kinetics (Control experiment) positive — In Vitro Transport
  • P-gp (ABCB1)
 digoxin
NPDI-WL-VKw Kratom (Mitragyna speciosa) The inhibitory effects of mitragynine on P-glycoprotein in vitro Control inhibition of P-gp digoxin transport by quinidine In Vitro Transporter Inhibition (Control experiment) positive — In Vitro Transporter Inhibition
  • P-gp (ABCB1)
 digoxin quinidine

Compound information from external resources

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