- Natural product: Kratom (Mitragyna speciosa)
- Associated study: The inhibitory effects of mitragynine on P-glycoprotein in vitro
In Vitro Transporter Kinetics Experiment
Control P-gp digoxin transport
Transport Activity was detected. Cutoff used —
(not provided)
digoxin 1326303
- P-gp (ABCB1)
Cell system Caco-2 cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
100000 cells / cm^2 per insert
Transwell® polycarbonate membrane cell culture insert
21
350 - 600 Ωcm^2
72 h
10 µM