- Natural product: Cannabis (Cannabis sativa)
- Associated study: Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes
In Vitro Enzyme Inhibition Experiment
Inhibition of 11-hydroxylation of delta-9-THC by sulfaphenazole
Inhibition was detected. Cutoff used —
Not provided
- CYP2C
Cell fraction Pooled human liver microsomes -7999662
Results
Table 1
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
10 microG
Commercially available
20 min
NADPH
NADPH regenerating system
64 µM
50 µM