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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-YQ1c2Q Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of cannabinol by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
cannabinol 11-hydroxycannabinol alpha-naphthoflavone
NPDI-8flCOQ Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Inhibition of 11-hydroxylation of cannabinol by sulfaphenazole In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C
cannabinol 11-hydroxycannabinol sulfaphenazole
NPDI-VpD-Xg Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of cannabinol by ketoconazole In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP3A
cannabinol 11-hydroxycannabinol ketoconazole
NPDI-PxRYvA Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids CBN-UGT1A10 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A10
cannabinol 11-hydroxycannabinol
NPDI-akOrWg Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids CBN-UGT1A9 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A9
cannabinol 11-hydroxycannabinol
NPDI-ToTRjw Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids CBN-UGT1A8 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A8
cannabinol 11-hydroxycannabinol
NPDI-Qoqt5Q Cannabis (Cannabis sativa) Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids CBN-UGT1A7 In Vitro Enzyme Kinetics positive — In Vitro Detectable Kinetic Metabolism
  • UGT1A7
cannabinol 11-hydroxycannabinol

Compound information from external resources

Resource Identifier
Google search YDKZOUNVEIGJPO-UHFFFAOYSA-N