alpha-naphthoflavone
InChIKey: VFMMPHCGEFXGIP-UHFFFAOYSA-N

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-5LuVNQ Kratom (Mitragyna speciosa) Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids Control Positive Inhibition for CYP1A2 In Vitro Enzyme Inhibition (Control experiment) positive — In Vitro Enzyme Inhibition
  • CYP1A2
phenacetin acetaminophen alpha-naphthoflavone
NPDI-THVK4A Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes No inhibition of 8-beta-hydroxylation of delta-9-THC by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
delta-9-tetrahydrocannabinol 8-beta-hydroxy-delta-9-tetrahydrocannabinol alpha-naphthoflavone
NPDI-RCBEtw Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of delta-8-THC by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
delta-8-tetrahydrocannabinol 11-hydroxy-delta-8-tetrahydrocannabinol alpha-naphthoflavone
NPDI-IQtjvw Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of delta-9-THC by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
delta-9-tetrahydrocannabinol 11-hydroxy-delta-9-tetrahydrocannabinol alpha-naphthoflavone
NPDI-EYnQkA Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes No inhibition of 7-alpha-hydroxylation of delta-8-THC by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
delta-8-tetrahydrocannabinol 7-alpha-hydroxy-delta-8-tetrahydrocannabinol alpha-naphthoflavone
NPDI-YQ1c2Q Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes Weak Inhibition of 11-hydroxylation of cannabinol by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
cannabinol 11-hydroxycannabinol alpha-naphthoflavone
NPDI-v8ghug Cannabis (Cannabis sativa) Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes No Inhibition of 8-hydroxylation of cannabinol by 7,8-benzoflavone In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A
cannabinol 8-hydroxycannabinol alpha-naphthoflavone

Compound information from external resources

Resource Identifier
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