Weak Inhibition of 11-hydroxylation of delta-9-THC by 7,8-benzoflavone CSV JSON

In Vitro Enzyme Inhibition Experiment

Weak Inhibition of 11-hydroxylation of delta-9-THC by 7,8-benzoflavone

Negligible Inhibition was detected.  Cutoff used —

Not provided

alpha-naphthoflavone

11-hydroxy-delta-9-tetrahydrocannabinol

  • CYP1A

Cell fraction Pooled human liver microsomes -7999662

Results

Table 1

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

10 microG

Commercially available

20 min

NADPH
NADPH regenerating system

64 µM

10 µM