Mitragynine inhibition of CYP1A2 CSV JSON

In Vitro Enzyme Inhibition Experiment

Mitragynine inhibition of CYP1A2

Inhibition was detected.  Cutoff used —

Not specified

3-cyano-7-ethoxycoumarin

mitragynine

3-cyano-7-hydroxycoumarin

  • CYP1A2 4312402

Recombinant expression system Not available
Cytochrome B5 Not available

Results

Furafylline is used as the positive control
(Table 2, Figure 2)

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.5 pmol/well

Commercially available

20 min

NADPH regenerating system