- Natural product: Cannabis (Cannabis sativa)
- Associated study: Enhanced biotransformation of theophylline in marihuana and tobacco smokers.
In Vivo Interaction Study
Decreased systemic exposure of Theophylline with Smoked Marihuana (non Tobacco smoker)
Increased systemic exposure was detected.
theophylline 1237049
caffeine 1134439
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
Parallel
Females
Males
Healthy alcohol drinking
7
5 males and 2 females
Drug or Natural Product Administration
Oral
orange juice
5 mg/kg
12h
Inhalation
plant
n/a