caffeine
InChIKey: RYYVLZVUVIJVGH-UHFFFAOYSA-N

Need public description.

Compound information managed by NaPDI

  • Green tea (Camellia sinensis)

None listed

None listed


ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-4v_54A Green tea (Camellia sinensis) Effects of repeated green tea catechin administration on human cytochrome P450 activity. In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP1A2
caffeine green tea leaf
NPDI-3VbSWA Goldenseal (Hydrastis canadensis) Repeated administration of berberine inhibits cytochromes P450 in humans CYP1A2 Experiment In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP1A2
caffeine berberine
NPDI-T6Zq4Q Goldenseal (Hydrastis canadensis) In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4 phenotypes CYP1A2 Experiment In Vivo Interaction negative — No Effect (based on bioequivalence limits)
  • CYP1A2
caffeine goldenseal root extract
NPDI-RUuAkA Cannabis (Cannabis sativa) Enhanced biotransformation of theophylline in marihuana and tobacco smokers. Decreased systemic exposure of Theophylline with Smoked Marihuana (Tobacco smoker) In Vivo Interaction positive — PK Interaction - Decreased systemic exposure
theophylline caffeine
NPDI-P9f-Mw Cannabis (Cannabis sativa) Enhanced biotransformation of theophylline in marihuana and tobacco smokers. Decreased systemic exposure of Theophylline with Smoked Marihuana (non Tobacco smoker) In Vivo Interaction positive — PK Interaction - Increased systemic exposure
theophylline caffeine
NPDI-6t3-aw Cannabis (Cannabis sativa) Enhanced biotransformation of theophylline in marihuana and tobacco smokers. Decreased systemic exposure of Theophylline with Smoked Tobacco (no Marihuana smoker) In Vivo Interaction positive — PK Interaction - Decreased systemic exposure
theophylline caffeine
NPDI-5GJkjQ Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 THC Inhibition of CYP1A2 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
theophylline caffeine delta-9-tetrahydrocannabinol
NPDI--MuxkQ Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 CBD Inhibition on CYP1A2 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
theophylline caffeine cannabidiol
NPDI-KKxwkg Cannabis (Cannabis sativa) Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450 11-OH-THC Inhibition of CYP1A2 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
theophylline caffeine 11-hydroxy-delta-9-tetrahydrocannabinol

Compound information from external resources

Resource Identifier
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