- Natural product: Cannabis (Cannabis sativa)
- Associated study: CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells
In Vitro Transporter Induction Experiment
CBD
Induction was detected. Cutoff used — Not specified
- P-gp (ABCB1)
Cell system Other cells
CEM/VLB100 cell line
Results
Estimated from Fig 1b and 1d. at 4 hr
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
mRNA expression
10^7 cells/mL
10 μM
Sigma-Aldrich
4, 8, 48 h
Rhodomine 123 uptake/retention assay