In Vivo Interaction Study
Secobarbital Plasma Concentrations Following Sodium Secobarbital Ingestion and 500 µg/kg CBD Pretreatment
No Effect (based on bioequivalence limits) was detected.
Values estimated from Figure 1. Original value was converted to ng/mL: Cmax (µg/mL): 2.75
|Sample||Compound measured||Measurement||Value||Study sequence||Additional information||N replicates|
"No subjects used drugs or medication habitually, but all had previously smoked marijuana. Subjects were instructed to fast at least four hours prior to the experimental session and to eat a light breakfast consisting of dry toast and juice. [...] All sessions were separated by at least one week."
0, 15, 30, 45, 60, 75, 90, 105, 120, 150, 180, 210, 240, 270, 300 min, 24, 48, and 72 h
Drug or Natural Product Administration
150 mg/70 kg