In Vitro Enzyme Inhibition Experiment

iHLM: CBN-diclofenac

Inhibition was detected.  Cutoff used — Not specified

diclofenac 1124300

cannabinol (cbn)


  • CYP2C9 4309227

Cell fraction Individual human liver microsomes


Tables 2 and 3

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

50 μg

Commercially available

250 μL

20 min

NADPH regenerating system

5 min

NADPH with precipitant