Inhibition of CYP2C19 by (-)-Epigallocatechin Gallate in HLM (Ki Determination) CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP2C19 by (-)-Epigallocatechin Gallate in HLM (Ki Determination)

Inhibition was detected.  Cutoff used — Ki determination

mephenytoin, (s)-

4-hydroxymephenytoin, (s)-

  • CYP2C19 4311137

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

Commercially available

100 µL

40 min

NADPH

Not available

Not available

14.5-58 µM

1-218 µM