- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibitory effects of various beverages on ritodrine sulfation by recombinant human sulfotransferase isoforms SULT1A1 and SULT1A3
In Vitro Enzyme Inhibition Experiment
Green tea inhibition of SULT1A3 using dopamine as the substrate
Inhibition was detected. Cutoff used — Not available
- SULT1A3
Recombinant expression system E.coli
Cytochrome B5 No
Results
The above results were observed at concentrations of 5 and 10%. At green tea 1%, dopamin sulfation was significantly inhibited by approximately 55% (estimated from Fig. 4B; P < 0.01).
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
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Experimental Conditions
In-house preparation
50 µL
10 min (pH 6.8)
PAPS
1 µM
1, 5, and 10%