Experiment #NPDI-d5Gm3Q CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition was detected.  Cutoff used — Not specified

3-cyano-7-ethoxycoumarin

mitragynine

3-cyano-7-hydroxycoumarin

  • CYP2C19 4311137

Recombinant expression system Not available
Cytochrome B5 Not available

Results

IC50 was not determined because inhibition was < 50%.
Tranylcypromine was used as a positive control.
(Table 2, Figure 2)

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.5 pmol/well

Commercially available

30 min

NADPH regenerating system