Mitragynine inhibition of CYP2C19 CSV JSON

Mitragynine inhibition of CYP2C19

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Recombinant expression system Not available
Cytochrome B5 Not available

IC₅₀ was not determined because inhibition was < 50%.
Tranylcypromine was used as a positive control.
(Table 2, Figure 2)

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Cell density

0.5 pmol/well

Test system preparation

Commercially available

Incubation time

30 min

Co-factors

NADPH regenerating system

NOTE