- Natural product: Goldenseal (Hydrastis canadensis)
- Associated study: Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine
In Vitro Transporter Inhibition Experiment
OCT2 Inhibition by Berberine (5-HT)
Inhibition was detected. Cutoff used — not specified
- OCT2 (SLC22A2)
Transfected / siRNA knock-out / injected cells MDCK transfected cells
Results
Table 2
Fig 3a final point estimate
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
24 well
2-3
5 min
37 deg C
10 μM
0.0001 to 1000 μM
Aladdin Co., Ltd. (Shanghai, China)