Control Positive Inhibition for CYP2C19 CSV JSON

In Vitro Enzyme Inhibition Experiment

Control Positive Inhibition for CYP2C19

Inhibition was detected.  Cutoff used —

IC50 = 45 μM

mephenytoin, (s)-

(s)-(+)-n-3-benzylnirvanol

4-hydroxymephenytoin, (s)-

  • CYP2C19 4311137

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Table S2

0.1 mg/ml

200 µL

60 min

NADPH

40 µM