2C9 Inhibition by Berberine CSV JSON

In Vitro Enzyme Inhibition Experiment

2C9 Inhibition by Berberine

Inhibition was detected.  Cutoff used — not specified

diclofenac 1124300

Berberine 19012197

4'-hydroxydiclofenac

  • CYP2C9 4309227

Cell fraction Pooled human liver microsomes -7999662

Results

Fig 4c estimation at 500 μM

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

0.5 mg/mL

Commercially available

30 min

NADPH

100 μ􏱂M

No NADPH with precipitant

10, 100, and 500 􏱂μ􏱂M