BCRP inhibition measured by accumulation CSV JSON

BCRP inhibition measured by accumulation

Object compound

Transporters involved

Test system used

Transfected / siRNA knock-out / injected cells HEK293 transfected cells

Table 1 - Values are expressed as percentage of control, mean ± SEM, n ≥ 4 for mitoxantrone accumulation

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Cell Culture Conditions

Density

7 x 10^5 cells/mL

Protein amount/well or concentration

200 μg/mL

Assay Conditions

Incubation time

90 min

Incubation temperature

37 deg C

Object concentrations tested

5 μM

NOTE